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herbicidal activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetolactate Synthase (ALS) (1) Bacterial (1) DNA/RNA Synthesis (1) Fungal (3) HPPD (2) Parasite (1) Proton Pump (1) Protoporphyrinogen IX oxidase (1) Reactive Oxygen Species (1) Succinate Dehydrogenase (1) Transketolase (2)
By Research Areas:	Cancer (1) Infection (3)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151604

Transketolase-IN-3	Transketolase	Others
Transketolase-IN-3 is a potent transketolase (TK) inhibitor. Transketolase-IN-3 has herbicidal activity and has inhibitory effects against Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). Transketolase-IN-3 can be used for the research of herbicides .

HY-N10260

Curvulinic acid

Others Others

Curvulinic acid is a phytotoxic compound, has herbicidal activity .

Curvulinic acid	Others	Others
Curvulinic acid is a phytotoxic compound, has herbicidal activity .

HY-148429

Antimalarial agent 17	Parasite	Others
Antimalarial agent 17 is an antimalarial agent, also acts as a herbicide. Antimalarial agent 17 is photosystem II inhibitor, shows post-emergence herbicidal activity equal to commercial herbicides .

HY-116489

Pyribenzoxim LGC-40863	Others	Others
Pyribenzoxim (LGC-40863) is a broad-spectrum herbicide. Pyribenzoxim has a higher safety level in bentgrass and a stronger herbicidal activity on grass weeds .

HY-155135

HPPD-IN-1	HPPD	Others
HPPD-IN-1 (compound II-3) is a HPPD inhibitor. HPPD-IN-1 shows inhibitory activity of Arabidopsis thaliana HPPD (AtHPPD) with an IC₅₀ value of 0.248 μM, which was superior to that of mesotrione (HY-12853) (0.283 μM) in vitro. HPPD-IN-1 shows excellent herbicidal activity against broadleaf and monocotyledonous weeds .

HY-163298

Herbicidal agent 2	Protoporphyrinogen IX oxidase	Others
Herbicidal agent 2 (compound 8d), a herbicide, is a protoporphyrinogen oxidase (PPO) inhibitor. Herbicidal agent 2 exhibits herbicidal activities against broadleaf and monocotyledon weeds .

HY-157025

Herbicidal agent 1

Others Others

Herbicidal agent 1 （(S)-6q）is a herbicidal agent with superior activity than its racemate .
HY-157024

Phytoene desaturase-IN-2

Others Others

PDS-IN-1 is a potent inhibitor of Oryza sativa phytoene desaturase (OsPDS), resulting in herbicidal activity .
HY-157471

PPO-IN-7

Others Others

PPO-IN-7 (compound 35) is a potent inhibitor of protoporphyrinogen oxidase (PPO). PPO-IN-7 shows herbicidal activity .

Herbicidal agent 1	Others	Others
Herbicidal agent 1 （(S)-6q）is a herbicidal agent with superior activity than its racemate .

Phytoene desaturase-IN-2	Others	Others
PDS-IN-1 is a potent inhibitor of Oryza sativa phytoene desaturase (OsPDS), resulting in herbicidal activity .

PPO-IN-7	Others	Others
PPO-IN-7 (compound 35) is a potent inhibitor of protoporphyrinogen oxidase (PPO). PPO-IN-7 shows herbicidal activity .

HY-108970

Bafilomycin D	Proton Pump Bacterial Fungal	Infection
Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity .

HY-163310

Transketolase-IN-5	Transketolase	Others
Transketolase-IN-5 (compound 6ba) is a transketolase inhibitor. Transketolase-IN-5 shows herbicidal activity for Amaranthus retroflexus, Setariaviridis, Digitaria sanguinalis .

HY-120183

Harzianopyridone	Fungal	Infection
Harzianopyridone is a compound that can be isolated from Trichoderma harzianum. Harzianopyridone is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 80 nM. Harzianopyridone has antifungal, antibacterial, and herbicidal activities .

HY-155465

HPPD-IN-2

HPPD Others

HPPD-IN-2 (compound 28) is a herbicide based on HPPD inhibitors. HPPD-IN-2 potently targets AtHPPD and exhibits enhanced safety in canola crops .

HPPD-IN-2	HPPD	Others
HPPD-IN-2 (compound 28) is a herbicide based on HPPD inhibitors. HPPD-IN-2 potently targets AtHPPD and exhibits enhanced safety in canola crops .

HY-149312

PPO-IN-3	Others	Others
PPO-IN-3 (Compound 8ad) is a PPO inhibitor with an K_I value of 0.67 nM. PPO-IN-3 has post-emergence herbicidal activity. PPO-IN-3 can be used for weed control .

HY-B1869

Metsulfuron-methyl
Metsulfuron-methyl is a systemic sulfonylurea herbicide and has been widely used to control broad-leaved weeds and annual grasses in rice, maize, wheat, and barley. Metsulfuron-methyl has highly efficient herbicidal activity and low mammalian toxicity .

HY-W422402

Foramsulfuron	Acetolactate Synthase (ALS)	Others
Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .

HY-163284

SDH-IN-12	Succinate Dehydrogenase Fungal	Infection
SDH-IN-12 (compound 9b) is a succinate dehydrogenase inhibitor, which exhibits activity against S. sclerotiorum and C. arachidicola, with EC₅₀s of 0.97 and 2.07 μM, respectively. SDH-IN-12 reveals no significant herbicidal activity against monocotyledonous and dicotyledonous plants .

HY-N11854

Brassicanate A sulfoxide	Others	Others
Brassicanate A sulfoxide has herbicidal activity. Brassicanate A sulfoxide inhibits the biosynthesis of essential amino acids in plants. Brassicanate A sulfoxide binds to dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins and transport inhibitor response 1 (TIR1), and reduces their activity. Brassicanate A sulfoxide can be isolated from Brassica oleracea .

HY-19828

Herboxidiene GEX1A	DNA/RNA Synthesis	Cancer
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .

HY-151095

Phytoene desaturase-IN-1	Reactive Oxygen Species	Others
Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (K_d: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production .

Herboxidiene GEX1A	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Biological Pesticide Research Cancer Agricultural Research	DNA/RNA Synthesis
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .

Curvulinic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Disease Research Fields Biological Pesticide Research Agricultural Research	Others
Curvulinic acid is a phytotoxic compound, has herbicidal activity .

Bafilomycin D	Structural Classification Natural Products Microorganisms Source classification	Proton Pump Bacterial Fungal
Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity .

Harzianopyridone	Structural Classification Natural Products Microorganisms Source classification	Fungal
Harzianopyridone is a compound that can be isolated from Trichoderma harzianum. Harzianopyridone is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 80 nM. Harzianopyridone has antifungal, antibacterial, and herbicidal activities .

Brassicanate A sulfoxide	Structural Classification Alkaloids Pyrrole Alkaloids Brassica oleracea L. Source classification Plants Brassicaceae	Others
Brassicanate A sulfoxide has herbicidal activity. Brassicanate A sulfoxide inhibits the biosynthesis of essential amino acids in plants. Brassicanate A sulfoxide binds to dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins and transport inhibitor response 1 (TIR1), and reduces their activity. Brassicanate A sulfoxide can be isolated from Brassica oleracea .

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herbicidal activity

Inhibitors & Agonists

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